Antiretroviral Therapy Adherence Level and Associated Factors Among HIV/AIDS Patients in Jimma Zone Government Health Facilities, ART Clinics, South-west Ethiopia

Aregash Hassen, Yasmin Mohammed


Optimal and strict adherence to Antiretroviral Viral Therapy a need for over the long period to achieve the goals of ART and obtain maximum benefits of ART. However, PLWHA find it very difficult to take ARVs drug as precisely as they should for a number of reasons. Therefore, this study aimed at examining the level of antiretroviral therapy adherence and identifying possible associated factors for ART adherence behavior in Jimma zone government ART facilities. A facility based cross-sectional study was  conducted in the ART clinics of Jimma zone governmental health facilities in which ARV treatment supplied from November 25/2015 – February 30/2016 for a period of 4 months. 352 adult PLWHA (190 female and 162 male) ranged in age from 15-62 years (Mean=37.1, SD= 8.95), with 100% response rate, were our study participants. Binary logistic regression was used to perform bivariate and multivariate analyses to determine the association between study variables and ART adherence status. 259(73.6%) participants were adherent (>=95%) and 93(26.4%) were non-adherent (<95%) to the prescribed dose of ARV drugs over the past seven days prior to the interview. The main reasons for skipping the prescribed ARV drugs were, busyness (78.5%), having too many pills (71%), felt depressed (68.8%), taking the drugs reminded HIV infected (66.7%), did not want other see (62.4%), and felt asleep(60.2%). The last stepwise regression analysis revealed that, educational status, knowledge of HIV/AIDS, use of additional drugs and access to reliable pharmacy were significantly associated with ART adherence status. So, efforts to maximize ART adherence should focus on addressing these associated significant factors.


ART Adherence; HIV/AIDS

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Alagaw, A., Godana, W, Taha, M., & Dejene, T. (2013). Factors Associated with Antiretroviral Treatment Adherence among Adult Patients in Wolaita Soddo Hospital. J Trop Dis 1, 125. Doi: 10.4172/2329-891X.1000125.

Amberbir, A., Woldemichael, K., Getachew, S., Girma, B., & Deribe, K. (2008). Predictors of Adherence to Antiretroviral Therapy Among HIV Infected Persons: A Prospective Study in Southwest Ethiopia. Available from: trez.

Ammassari, A., PaolaTrotta, M., Mul, R. (2005). Correlates and Predictors of Adherence to HAART. Journal of Acquired Immune Deficiency Syndrome, 31(3): 123- 127.

Asefa T, Taha M, Dejene T, Dube L. (2013). Determinants of Defaulting from Antiretroviral Therapy Treatment in Nekemte Hospital, Eastern Wollega Zone, Western Ethiopia. Public Health Research, 3(5): 130–5.

Assefa, Y., Worku, A., Wouters, E., Koole, O., Hailemariam, D., Van Damme, W. (2012). Simplified Tools for Measuring Retention in Care in Antiretroviral Treatment Program in Ethiopia: Cohort and Current Retention in Care. PLoS One, 7(6): e38555. Doi:10.1371/journal.pone.0038555.

Ayalu, A.R. & Sibhatu, B. (2012). Determinants of Adherence to Antiretroviral Therapy Among HIV-Infected Patients in Africa. AIDS Research and Treatment, 20.

Ayele A, Tefera B, Fisehaye A, Sibhatu B. (2010). Predictors of Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in Resource Limited Setting of Southwest Ethiopia. AIDS Research and Therapy, 7: 39.

Bach X. T., Long T. N., Nga H. N., Quynh V. H. and Jongnam H. (2013). Determinants of Antiretroviral Treatment Adherence Among HIV/AIDS Patients: A Multisite Study. Glob Health Action, 6: 19570-

Carrieri, P., Cailleton, V., Le Moing, V., Spire. B., Delllanonica, P., Bouvet, E., Raffi, F., Journot, V., Moatti, J.P., & APROCO Study Group. (2001). The Dynamic of Adherence to Highly Active Antiretroviral Therapy: Results from the French National APROCO cohort. J Acquir Immune Defiic Syndr, 28: 232–39.

Chaka, T. E., Abeya, S. G., Adlo, A. M., Abebe, T. W., Hamuse, S. D., et al. (2016). Antiretroviral Therapy: Level of Adherence and Its Determinants Among Patients on Treatment in Different Health Facilities. A Cross Sectional Study in Oromia Regional State, Ethiopia. J AIDS Clin Res, 7(629). Doi: 10.4172/2155-6113.1000629.

Chesney, M. A. (2000). Factors Affecting Adherence to Antiretroviral Therapy. Clinical Infectious Diseases, 30(2): 171-176.

CSA. (2011). Ethiopia Demographic and Health Survey 2011. Addis Ababa, Ethiopia.

Deribe K, Hailekiros F, Biadgilign S, Amberbir A, Beyene BK. (2008). Defaulters from Antiretroviral Treatment in Jimma University Specialized Hospital, Southwest Ethiopia. Tropical Medicine & International Health, 13(3): 328–33.

FMOH. (2006). Disease Prevention and Control Department, AIDS in Ethiopia, 6th Edition, Addis Ababa. FMOH.

Ford N, Boulle A, Egger M. (2016). Accounting for and Responding to HIV-Associated Mortality. AIDS (London, England), 30(3): 521–3.

Gesesew HA, Ward P, Woldemichael K, Mwanri L. (2017). Prevalence, Trend and Risk Factors for Antiretroviral Therapy Discontinuation Among HIV-Infected Adults in Ethiopia in 2003-2015. PLoS ONE, 12(6): e0179533.

Health, F. H. P. and C. O. F. M. (2009). Guidelines for Implementation of HIV/AIDS Case Management in Ethiopia: 1–71.

Heyer, A., & Ogunbanjo, G. A. (2006). Adherence to HIV Antiretroviral Therapy. Part I: A Review of Factors that Influence Adherence. Open forum.

James E. B., Joe W. K., and Chadwick C. (2001). Organizational Research: Determining Appropriate Sample Size in Survey Research. Information Technology, Learning, and Performance Journal, 19(1).

Kalibala Samuel, Nrupa Jani and Getachew Kassa. (2016). “Algorithms for HIV Care and Treatment in Ethiopia,” HIVCore Final Report. Washington, DC: USAID | Project Search: HIVCore.

Markos, E., Worku, A. & Davey, G. (2008). Adherence to ART in PLWHA at Yirgalem Hospital, South Ethiopia. Ethiop. J. Health Dev., 22(2): 174–179.

Melissa, W., Maman, S., Earp, J. A., Eng, E., Setel, P., et al. (2009). It‘s All the Time in My Mind: Facilitators of Adherence to Antiretroviral Therapy in a Tanzanian Setting. Social Science & Medicine, 68: 1793-1800.

Mills, E. J., Nachega, J. B., Bangsberg, D. R., Singh, S., Rachlis, B., et al. (2006). Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators. PLoS medicine, 3(11): 438. Available at: 1637123&tool=pmcentrez rendertype=abstract [Accessed May 26, 2013].

Morten S, Catherine C, Kundai N, Constance N and Simon G. (2011). Contextual and Psychosocial Influences on Antiretroviral Therapy Adherence in Rural Zimbabwe: Towards A Systematic Framework for Program Planners. Int J Health Plann Mgmt 2011; 26: 296–318.

ORHB. Oromia Regional Health Bureau Report 2013/14.

Paterson, D.L., Swindells, S., Mohr, J., Brester, M., Vergis, E., Squire, C. et al., (2000). Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection. Ann Intern Med, 133: 21-30.

Sarna, A., Luchters, S., Geibel, S., Chersich, M.F., Munyao, P., Kaai, S., et al. (2008). Short- and Long-Term Efficacy of Modified Directly Observed Antiretroviral Treatment in Mombasa, Kenya: A Rando- Mized trial. J Acquir Immune Defic Syndr, 48: 611–619.

Sileshi Garoma Abeya, Abebe Megerso Adlo, Tolesa Eticha Chaka, Tilay Worineh Abebe, et al., (2017). Anti-Retroviral Therapy in Public Health Institutions of Oromia Region: A qualitative study. Public Health International, 2(1): 51-59.

Simoni et al. 2008. Strategies for Promoting Adherence to Antiretroviral Therapy: A Review of the Literature. Current Infectious Disease Report, 10: 515-521

Tadios Y, Davey G. (2006). Antiretroviral Treatment Adherence and Its Correlates Among People Living with HIV/AIDS on Highly Active Antiretroviral Therapy in Addis Ababa, Ethiopia. Ethiopian Medical Journal, 44(2): 237-244.

UNAIDS. (2016). Global AIDS Update, 2016.

Wang H, Wolock TM, Carter A, Nguyen G, Kyu HH, Gakidou E, et al. (2016). Estimates of Global, Regional, and National Incidence, Prevalence, and Mortality of HIV, 1980–2015: The Global Burden of Disease Study 2015. Lancet HIV, 3(8): e361–87.

WHO. (2003). Adherence to Long-Term Therapy: Evidence for Action. Geneva.

WHO. (2006). Antiretroviral Therapy for HIV Infection in Adults and Adolescents. Recommendations for a Public Health Approach.

WHO. (2011). Towards Universal Access: Scaling up Priority HIV/AIDS Interventions in the Health Sector. Progress Report 2010. Geneva.

WHO.(2008). Determinants of Adherence to Antiretroviral Treatment: An Explorative Study at Health Facilities in Ethiopia and Uganda. INRUD.



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