Some Indicators of Blood of Rats Poisoned with Pesticide Karate

Mirkhamidova Paridakhon, Tuychiyeva Dilfuza, Parpiyeva Mashkhura, Babakhanova Dilnoza, Alimova Ra’no

Abstract


An artificially reconstructed karate pesticide leads to cytopsy of blood corpuscles and a shift of the Leiko formula to the right. In this case, the erythrocyte indices, the color index of erythrocytes and the average hemoglobin content, as well as the erythrocyte sedimentation rate, significantly increase. A decrease in the number of corpuscles with increased erythrocyte indices (CP and DES), accompanied by granulocytopenia, agranulocyte and accelerated erythrocyte sedimentation rate are additional evidence of B12-deficiency and folate-deficiency anemia. The research of the parameters of peripheral blood poisoned with karate of rats at introduction of its per os RAF is shown that all studied indicators of approximately identical size with indicators of blood of intact rats.


Keywords


Pesticides; Antioxidants; Vegetable Antioxidant Factor; Albumine, Globulins; Leukocytes; Lymphocytes; Monocytes; Peroxide Oxidation of Lipids; Neutrophils; Vegetable Antioxidant Drug; So-So Molecular Peptides; Erythrocytes; Hemoglobin; Thrombocytes; Eosin

Full Text:

PDF

References


Abdulkadirov K.M. Depressiya gemopoeza v rezultate proizvodstvennix intoksikatsiy Klinicheskaya gematologiya[Depression of hematopoiesis as a result of industrial intoxication Clinical hematology] / K.M. Abdulkadirov Spravochnik. —Piter, 2006. —448 s.

Alimbabaeva N.T., Mirxamidova P., Isabekova M.A., Zikiryaev A., Fayzullaev S.S. Deystvie ostatochnix kolichestv karate na aktivnost mitoxondrialnix fermentov gepatotsitov[Effect of residual amounts of karate on the activity of mitochondrial enzymes in hepatocytes]. Uzbekskiy biologicheskiy jurnal T.: «Fan» №4 - 2005, s. 15-19.

Alimbabaeva N.T., Xalitova R.A., Mirxamidova P.M., Tutundjan A.A., Zikiryaev A., Fayzulaev S.S. Deystvie karate na POL v mitoxondriyax i mikrosomax pecheni kris[The effect of karate on lipid peroxidation in mitochondria and microsomes of rat liver].T.: «Fan» №6 -2005, s.34– 37.

Axmedjanov K. Sostoyanie nekotorix pokazateley perifericheskoy krovi pri vozdeystvii fosfororganicheskix soedineniy maloy intensivnosti v eksperimente//Aktualnie voprosi gigieni primeneniya pestitsidov v razlichnix klimato- geograficheskix zonax[The state of some indicators of peripheral blood under the influence of organophosphorus compounds of low intensity in the experiment // Actual problems of hygiene of the use of pesticides in different climatic and geographical zones]//Erevan: Ayastan - 1976.-S.129-131.

Bardov V.G., Leonenko O.B., Omelchuk S.T., Sasinovich L.M. Protsessi svobodno-radikalnogo perekisnogo okisleniya lipidov v mexanizme deystviya sinteticheskix piretroidov[The processes of free radical lipid peroxidation in the mechanism of action of synthetic pyrethroids] // Sovremennie problemi toksikologii.— M.: - 1999. -№1.- S. 37 - 43.

Burkaskaya E.N., Lisina G.G., Karpenko V.N. Laboratornaya diagnostika intoksikatsiy pestitsidami[Laboratory diagnostics of pesticide intoxication]. — M.: Meditsina - 1978. —128 s.

Vigovskaya Ya.I., Loginskiy V.E., Mazurok A.S. Gematologicheskie sindromi v gematologicheskoy praktike[Hematological syndromes in hematological practice]// Kiev: Zdorovya - 1981. —S. 296.

Gratsianskaya L.R., Kovshilo. V.E. Spravochnik po professionalnoy patologii[Handbook of Occupational Pathology]—L.: Meditsina - 1981.—373 s.

Eliseeva. Yu.Yu. Analizi. Polniy spravochnik[Complete reference].-M.: Eksmo - 2007.-768s

Koksharyova N.V., Vekovshinina S.V., Shushurina N.A., Krivenchuk V.E.. Sinteticheskie piretroidi: mexanizm neyrotoksicheskogo deystviya, poisk sredstv lecheniya ostrix otravleniy. // Sovremennie problemi toksikologii[Synthetic pyrethroids: the mechanism of neurotoxic action, the search for remedies for the treatment of acute poisoning. // Modern problems of toxicology]. —2000. —№3 —S.21-25

Komilov B.O. Vliyanie gerbesidnix preparatov na kartinu krovi/Meditsinskie nauki[The influence of herbicidal preparations on the blood picture / Medical sciences], 2018 g./https//cyberleninka.ru

Lyubina A. Ya., i dr. Klinicheskie laboratornie issledovaniya[Clinical laboratory research]. M.: Meditsina - 1984. S. 288.

Melnikov N.N. Pestitsidi: Ximiya, texnologiya, primenenie[Pesticides: Chemistry, technology, application].–M.: Ximiya - 1987., 710 s.

Menshikov V.V. Laboratornie metodi issledovaniya v klinike [Laboratory research methods in the clinic]. Spravochnik. —M.: Meditsina -1987. —365 s.

Muxin.A.P., Sivkov I. G. Yadoximikati v s/xi sanitarnaya praktika [Pesticides in agriculture and sanitary practice] L.: Meditsina - 1974.g.-128c.

Oslopov V.N., Sadikov A.R., Abdulxakov A.R. Klinicheskaya laboratornaya diagnostika [Clinical laboratory diagnostics] -3-e izd. - M.: MEDpress-infor-2005.-64s

Tuychieva D. S., Ruzmatov E. Yu, Jaynakov M. Deystvie pestitsidov na funksionalnoe sostoyanie mitoxondriy pecheni beremennix kris i ix embrionov [Effect of pesticides on the functional state of liver mitochondria in pregnant rats and their embryos]// Moskva, Visshaya shkola, may (9), 2017 g, str.16-17

siniko T.F. Analizi govoryat o vashem zdorove[Analyzes tell about your health]. M.: Feniks, 2003 – 250s.

Cherkes F.K. Mikrobiologiya[Microbiology] M.: Meditsina. -1986 – 300 s.

Chirkin A.A. i dr Diagnosticheskiy spravochnik terapevta. Klinicheskie simptomi prognozirovaniya obsledovaniya bolnix, interpretatsiya dannix[Diagnostic reference book of the therapist. Clinical symptoms of predicting examination of patients, interpretation of data]. Minsk.: Belarus - 1993. – 688 s.

Shulyak V.G. Metodologichni pidxodi do osinki gematotoksichnoi dii pestitsidiv pri ix gigienichnomu normuvanni //Aktualni problemi ekogigieni i toksikologii[Methodological Approach to Assessment of Hematotoxic Diii Pesticides in Case of ix Hygienic Norms // Actual Problems of Ecology and Toxicology]: Materiali naukovo-praktichn. konf. 28-29 travnya, 1998.-Kiiv., Ch. 1., S. 246-249.

Alavanja M.C. Occupational pesticide exposures and cancer risk: a review / M.C. Alavanja, M.R. Bonner // J. Toxicol. Environ. Health B: Crit. Rev. —2012. —15. —R. 238–263.

Das R., Berkrnpan S., Vergara X., Sutton P. Pyrethroid pesticide illnesses in occupational settings: [North American Congress of clinical toxicology Annual Meeting, Monreal, Oct 4-9, 2001]// S. Toxicol. Clin Tixicol. -2001.- 39, №5— P. 476.

Konopska L., Gorski T., Zdiechowska H. et al. Spostrzezenia kliniczne dotyczace niedokrwistosci aplastycznej wywolanej przez weglowodory chlororganiczne. -—Pol. tyg. lek. - 1982. —37(34-35). —P. 1003-1006.

Morgan Donald P., Stockdale Earl M., Roberts Robert J. et al. Anemia associated with exposure to Hndane.//Arch. Environ Health -1980.-35 (5).

P. 307—310.

Michelle C. Residential Pesticides and Childhood Leukemia: A Systematic Review and Meta-Analysis / C.T. Michelle, T.W. Donald, D. Krewski // Environmental Health Perspectives. —2010. —118(1). —R. 33–41.

Priebe L., Friedrich M. Benndorf K. Functional interaction between K (ATP) channels and the Na+-K+ pump in metabolically inhibited cells of the guinea-pig. // J. Physiol. —1996. —V. 492, № 2. —P. 405—417

Pesticide Exposureas a Risk Factor for Myelodysplastic Syndromes: A Meta-Analysis Based on 1,942 Cases and 5,359 Controls. Published: October 21, 2014 / J. Jin, M. Yu, C. Hu et al.] http://dx.doi.org/10.1371/journal.pone.0110850

Risk of aplastic anemia and pesticide and other chemical exposures / N. Prihartono, D. Kriebel, S.Woskie fct al.] // Asia Pac. J. Public Health. —2011. —23(3). —R. 369–377.

Rhodes C.J. Book: Toxicology of the Human Environment — the critical role of free radicals, Taylor and Francis, London – 2000 – R.230.

Roberts H.J. Aplastic anemia and red cell aplasia due to pentachlorphenol. —South. Med. J. _1983. —76 (1). —P. 45 —48.

Rugman P.P., Cossick R. Aplastic anemia associated with organochlorine pesticide: case reports and review of evidence. — J. Clin. Pathol. —1990. —43(2). —P. 98-101.

Sudakin D.S., Wagner S.I. Human pesticide exposures: Trends and informational needs. [North American Congress of clinical toxicology Annual Meeting, Monreal, Oct 4—9, 2001] //S. Toxicol. Clin Tixicol. —2001. —39, №5. —P. 528.

http:/ref.net.ua/work/det-18975.

http://revolution.allbest.ru/medicine/00011682_0.html




DOI: http://dx.doi.org/10.18415/ijmmu.v7i7.1897

Refbacks

  • There are currently no refbacks.


Copyright (c) 2020 International Journal of Multicultural and Multireligious Understanding

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

International Journal of Multicultural and Multireligious Understanding (IJMMU) ISSN 2364-5369
https://ijmmu.com
editor@ijmmu.com
dx.doi.org/10.18415/ijmmu
facebook.com/ijmmu
Copyright © 2014-2018 IJMMU. All rights reserved.